Short Description
Giant Knotweed Extract polydatin is the glycoside of resveratrol isolated from the Chinese herb Polygonum cuspidatum.Polydatin is an effective candidate drug for the protection of photo-inflammation. Polydatin exhibitstherapeutic potential for vascular dementia, most likely due to its anti-oxidant activity and the directprotection of neurons.Polygonum is one of the plants of polygonaceae. It is native to east Asia and widely distributed in China. Knotweed is used in traditional Chinese and Japanese medicine to treat a variety of ailments, including fungal infections, skin inflammation, cardiovascular disease and liver disease.
Resveratrol and emodin are the main functional components of polygonum cuspidatum. Studies have shown that resveratrol and emodin exhibit a wide range of antioxidant properties, such as LDL cholesterol oxidation and lipid peroxidation. Resveratrol has also been shown to contribute to cardiovascular health and blood circulation, relieve pain, clear away heat, damp, poison and phlegm. Other ingredients including dananone, emodin methyl ether and rhein have anti-inflammatory, arthritic and antimicrobial activities.
Product Description
Product Name: Giant knotweed extract
Latin Name: Polygonum Cuspidatum
Category: Plant Extracts
Effective components: Resveratrol
Product specification: 50%, 98%
Analysis: HPLC
Quality Control : In House
Formulate: C14H12O3
Molecular weight: 228.25
CAS No: 501-36-0
Appearance: Off-white fine powder/off-white granule with characteristic odor.
Identification: Passes all criteria tests
Storage: keep in cool and dry place, well-closed, away from moisture or direct sunlight.
Volume Savings: Sufficient material supply and stable supply channel of raw material in north China.
| Certificate Of Analysis | |||
| Product name | Giant knotweed extract | Botanical Source | Polygonum cuspidatum. |
| Solvents Residue | Water&Ethanol | Part Used | Root&Stam |
| ITEMS | SPECIFICATION | METHOD | TEST RESULT |
| Physical&Chemical Data | |||
| Color | Off-White | Organoleptic | Qualified |
| Ordour | Characteristic | Organoleptic | Qualified |
| Appearance | Fine Powder | Organoleptic | Qualified |
| Analytical Quality | |||
| Identification | Identical to R.S. sample | HPTLC | Identical |
| Assay(L-5-HTP) | ≥98.0% | HPLC | 98.63% |
| Loss on Drying | 5.0% Max. | Eur.Ph.7.0 [2.5.12] | 3.21% |
| Total Ash | 5.0% Max. | Eur.Ph.7.0 [2.4.16] | 3.62% |
| Sieve | 100% pass 80 mesh | USP36<786> | Conform |
| Loose Density | 20~60 g/100ml | Eur.Ph.7.0 [2.9.34] | 53.38 g/100ml |
| Tap Density | 30~80 g/100ml | Eur.Ph.7.0 [2.9.34] | 72.38 g/100ml |
| Solvents Residue | Meet Eur.Ph.7.0 <5.4> | Eur.Ph.7.0 <2.4.24> | Qualified |
| Pesticides Residue | Meet USP Requirements | USP36 <561> | Qualified |
| Heavy Metals | |||
| Total Heavy Metals | 10ppm Max. | Eur.Ph.7.0 <2.2.58> ICP-MS | 1.388g/kg |
| Lead (Pb) | 3.0ppm Max. | Eur.Ph.7.0 <2.2.58> ICP-MS | 0.062g/kg |
| Arsenic (As) | 2.0ppm Max. | Eur.Ph.7.0 <2.2.58> ICP-MS | 0.005g/kg |
| Cadmium(Cd) | 1.0ppm Max. | Eur.Ph.7.0 <2.2.58> ICP-MS | 0.005g/kg |
| Mercury (Hg) | 0.5ppm Max. | Eur.Ph.7.0 <2.2.58> ICP-MS | 0.025g/kg |
| Microbe Tests | |||
| Total Plate Count | NMT 1000cfu/g | USP <2021> | Qualified |
| Total Yeast & Mold | NMT 100cfu/g | USP <2021> | Qualified |
| E.Coli | Negative | USP <2021> | Negative |
| Salmonella | Negative | USP <2021> | Negative |
| Packing&Storage | Packed in paper-drums and two plastic-bags inside. | ||
| N.W: 25kgs | |||
| Store in a well-closed container away from moisture, light, oxygen. | |||
| Shelf life | 24 months under the conditions above and in its original packaging. | ||
Product Function
Resveratrol weight loss, Resveratrol is naturally occurring phytoalexin produced by some higher plants in response to injury or fungal in fection. Phytoalexins are chemical substances produced by plants as a defense against in faction by pathogenic microorganisms,Natural Resveratrol may also have alexin-like activity for humans. Epidemiological, in vitro and animal studies suggest that a high resveratrol intake is associated with a reduced incidence of cardiovascular disease, and a reduced risk for cancer.
Cardiovascular – Resveratrol decreases the viscosity of the blood and acts as anticoagulant to thin blood, effective in treating cardiovascular disease by reducing thrombosis and embolisms that can block arteries and lead to myocardial and cerebral infarctions.
Cancer – Resveratrol has been found to reduce tumor volume, tumor weight Weight Loss – resveratrol is the most potent natural compound mimicking the positive effect of calorie restriction.
Antioxidant resveratrol prevent aging by protecting cellular free-radical damage.
kill Lyme bacteria.
Antimicrobial – To inhibit the growth of staph,salmonella the dosage. inhibit the growth of influ.
We hereby declare that, to the best of our knowledge, this product was not produced from or with GMO plant material.
BY PRODUCTS & IMPURITIES STATEMENT
We hereby declare that, to the best of our knowledge, this product does not contain and was not manufactured with any of the following substances:
Parabens
Phthalates
Volatile Organic Compounds (VOC)
Solvents and Residual Solvents
GLUTEN FREE STATEMENT
We hereby declare that, to the best of our knowledge, this product is gluten-free and was not manufactured with any ingredients containing gluten.
(BSE)/ (TSE) STATEMENT
We hereby confirm that, to the best of our knowledge, this product is free of BSE/TSE.
CRUELTY-FREE STATEMENT
We hereby declare that, to the best of our knowledge, this product has not been tested on animals.
KOSHER STATEMENT
We hereby confirm that this product has been certified to Kosher standards.
VEGAN STATEMENT
We hereby confirm that this product has been certified to Vegan standards.
FOOD ALLERGEN INFORMATION
| Component | Present in the product |
| Peanuts (and/or derivatives,) e.g., protein oil | No |
| Tree Nuts (and/or derivatives) | No |
| Seeds (Mustard, Sesame) (and/or derivatives) | No |
| Wheat, Barley, Rye, Oats, Spelt, Kamut or their hybrids | No |
| Gluten | No |
| Soybeans (and/or derivatives) | No |
| Dairy (including lactose) or Eggs | No |
| Fish or their products | No |
| Shellfish or their products | No |
| Celery (and/or derivatives) | No |
| Lupin (and/or derivatives) | No |
| Sulphites (and derivatives) (added or > 10 ppm) | No |
