NMN (Nicotinamide mononucleotide): The full name is “β-nicotinamide mononucleotide”, which is a naturally occurring biologically active nucleotide. There are two irregular forms of NMN, α and β; β isomer is the active form of NMN with a molecular weight of 334.221 g/mol. Because nicotinamide belongs to vitamin B3, NMN Powder belongs to the category of vitamin B derivatives. It is widely involved in many biochemical reactions of the human body and is closely related to immunity and metabolism.
Dietary Supplement Nicotinamide Mononucleotide (NMN and β-NMN) is a nucleotide derived from ribose and nicotinamide. A long-term study indicates that NMN can slow down the physiologic decline in ageing.
NMN Food Grade produced by Insen belongs to Vitamin B, participating in metabolism in the body.
NMN Food Grade could be used as feed and human nutrition, booth the growth and strengthen the immunity.
The substances inherent in the human body are also rich in some fruits and vegetables. In the human body, nicotinamide mononucleotide is the most direct precursor of NAD+, and its function is manifested through NAD+. NAD+ is also called Coenzyme I, and its full name is nicotinamide adenine dinucleotide. It exists in every cell and participates in thousands of reactions. In a variety of cellular metabolic reactions, nicotinamide adenine dinucleotide (NAD) molecules play an important role and are an important support for cells to maintain vitality.
The decline of NAD in the aging process is considered to be the main cause of diseases and disability, such as hearing and vision loss, cognitive and motor dysfunction, immune deficiency, arthritis, metabolic disorders and cardiovascular diseases caused by dysregulation of autoimmune inflammation. Therefore, supplementation of Beta NMN increases the NAD+ content in the body, thereby delaying, improving, and preventing various phenotypes related to aging, or age-induced metabolic disorders, senile diseases, etc.
Production Method
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Semi-Fermentation
Synthesizing Niacinamide ribose chloride first, and then produce it into NMN Nicotinamide Mononucleotide by fermentions.
Disadvantages: Enzyme protein impurities that are harmful to the human body will be produced during the production process, and the enzyme protein impurities must be strictly controlled.
Advantages: The purity is slightly higher than the purity of the synthetic method. |
| Synthetic
Aogu NMN Food Grade is chemically synthesized from beginning to end
Disadvantages: Genotoxic impurities are produced and solvent remains. Advantages: All impurities are very clear at a glance, They can be tested by HPLC. |
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Difference of NMN NAD NR
NAD+ is an important coenzyme in the mitochondria for aerobic oxidation and metabolism of tricarboxylic acid cycle to generate energy molecular ATP, so that the three types of nutrients obtained by the human body: sugar, fat and protein, are transformed into the energy required by the human body. However, due to its large molecular weight, it is difficult for NAD+ to penetrate the cell membrane and enter the cell, so it cannot be directly taken up.
Most of the oral NR is not converted into NMN, but is digested into NAM, failing to bypass the restriction of the rate-limiting enzyme NAMPT in the salvage synthesis pathway, and the ability to supplement NAD+ is limited.
Aogu NMN Nicotinamide Mononucleotide bypasses the bottleneck of the NAMPT rate-limiting enzyme and can quickly replenish NAD+ in the body, which is the best and ideal supplement method. NMN can quickly enter the body within 10 minutes, and after 30 minutes it is absorbed by the organs of the body and converted into NAD+, which can quickly replenish NAD+ in the body
Aogu Biotech, the professional NMN Supplement in China, provide 99%min purity, want to know more? Contact Aogu Biotech at your earliest convenience.
XI’AN AOGU BIOTECH CO.,LTD is devoted into the research and innovation in natural nutritional supplements ingredients. Our own factory and lab with the strict quality control system to ensure quality stability and real price of NMN (Nicotinamide mononucleotide). At the same time, we have our own source for the raw material to make sure the production ability.