Description:
Synonym(s):6-(1-Piperidinyl)pyrimidine-2,4-diamine 3-oxide,6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide
Empirical Formula (Hill Notation):C9H15N5O
CAS Number:38304-91-5
Molecular Weight:209.25
EC Number:253-874-2
Minoxidil applied to the scalp is used to stimulate hair growth in adult men and women with a certain type of baldness. The exact way that this medicine works is not known.
If hair growth is going to occur with the use of minoxidil, it usually occurs after the medicine has been used for several months and lasts only as long as the medicine continues to be used. Hair loss will begin again within a few months after minoxidil treatment is stopped.
In the U.S., this medicine is available without a prescription.
Uses
Minoxidil solution and foam are used to help hair growth in the treatment of male pattern baldness. It is not used for baldness at the front of the scalp or receding hairline in men. The foam and 2 percent minoxidil solution is also used to help hair growth in women with thinning hair.Minoxidil belongs to a class of drugs known as vasodilators. It is not known how minoxidil causes hair growth. This medication is not used for sudden/patchy hair loss, unexplained hair loss (for example, if you have no family history of hair loss), or hair loss after giving birth.Do not use this product if you are 18 years old or younger.
Application
Minoxidil has been used as test drug:
in dermal papilla spheroid model, to study the effect of hair regeneration
administered orally to experimental rats, in the approach to identify biomarkers of drug induced vascular injury
administered via oral gavage to nonhuman primate model in order to study its effect on tilt responses
Biochem/physiol Actions
Minoxidil is originally used to treat hypertension, which also induces hypertrichosis. It is considered as a potent drug for treating androgenetic alopecia.
Activates ATP-activated K+ channels; vasodilator; slow or stop hair loss and promote hair regrowth.
Features and Benefits
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates.
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages.
XI’AN AOGU BIOTECH CO.,LTD is devoted into the research and innovation in natural nutritional supplements ingredients. Our own factory and lab with the strict quality control system to ensure quality stability and real price of Minoxidil. At the same time, we have our own source for the raw material to make sure the production ability.