Name: Diosmin
CAS#: 520-27-4
Botanical Source: Immature bitter orange
Specification: EP, HPLC 90%–98%, Micronized Powder or Granule
Function & Application: Diosmin can protect blood vessel, enhance blood vessel tension, reduce capillary permeability, strengthen its resistance, invrease lymphatic drainage speed and its effect of contraction.
| TEST ITEM | STANDARD | RESULT |
| Appearance | Greyish-yellow or light yellow hygroscopic powder | Complies (Visual) |
| Melting point | 277℃-278℃ | Complies(Melting point apparatus) |
| Identification | (a)(b) Must Positive | Complies |
| Solubility | ||
| – in water | Insoluble | Complies |
| – in dimethyl sulfoxide | Soluble | Complies |
| – alcohol | Insoluble | |
| – dilute solutions of alkali hydroxides | Soluble | |
| Residue on ignition | ≤0.5% | Complies |
| Mesh size | 100% pass 80 mesh/2000 mesh | Complies |
| Iodine | ≤0.1% | Complies (Potentiostat) |
| Related substances | ||
| – acetoisovanillone | ≤0.5% | Complies (HPLC) |
| – hesperidin | ≤4.0% | Complies (HPLC) |
| – isorhoifolin | ≤3.0% | Complies (HPLC) |
| – 6-iododiosmin | ≤0.6% | Complies (HPLC) |
| – linarin | ≤3.0% | Complies (HPLC) |
| – diosmetin | ≤2.0% | Complies (HPLC) |
| – unspecified impurities | ≤0.4% | Complies (HPLC) |
| – total | ≤8.5% | Complies (HPLC) |
| Heavy metals | 90%—102% | Complies (HPLC) |
| Water | ≤6.0% | Complies (K.F) |
| Residual solvents | ||
| – methanol | ≤3000ppm | Complies (HPGC) |
| – acetic acid | ≤5000ppm | Complies (HPGC) |
| – pyridine | ≤200ppm | Complies (HPGC) |
| Assay | ||
| MICROBIOLOGICAL TEST | STANDARD | RESULT |
| Total microbial count | ≤1000cfu/g | Complies |
| Yeast & mold | ≤100cfu/g | Complies |
| E.Coli | Negative | Negative |
| Salmonella | Negative | Negative |
GMO STATEMENT
We hereby declare that, to the best of our knowledge, this product was not produced from or with GMO plant material.
BY PRODUCTS & IMPURITIES STATEMENT
We hereby declare that, to the best of our knowledge, this product does not contain and was not manufactured with any of the following substances:
Parabens
Phthalates
Volatile Organic Compounds (VOC)
Solvents and Residual Solvents
GLUTEN FREE STATEMENT
We hereby declare that, to the best of our knowledge, this product is gluten-free and was not manufactured with any ingredients containing gluten.
(BSE)/ (TSE) STATEMENT
We hereby confirm that, to the best of our knowledge, this product is free of BSE/TSE.
CRUELTY-FREE STATEMENT
We hereby declare that, to the best of our knowledge, this product has not been tested on animals.
KOSHER STATEMENT
We hereby confirm that this product has been certified to Kosher standards.
VEGAN STATEMENT
We hereby confirm that this product has been certified to Vegan standards.
FOOD ALLERGEN INFORMATION
| Component | Present in the product |
| Peanuts (and/or derivatives,) e.g., protein oil | No |
| Tree Nuts (and/or derivatives) | No |
| Seeds (Mustard, Sesame) (and/or derivatives) | No |
| Wheat, Barley, Rye, Oats, Spelt, Kamut or their hybrids | No |
| Gluten | No |
| Soybeans (and/or derivatives) | No |
| Dairy (including lactose) or Eggs | No |
| Fish or their products | No |
| Shellfish or their products | No |
| Celery (and/or derivatives) | No |
| Lupin (and/or derivatives) | No |
| Sulphites (and derivatives) (added or > 10 ppm) | No |
