What is Red Clover extract?
Red clover is a member of the legume family – the same class of plants where we find chickpeas and soybeans. Red clover extract are used as dietary supplements for their high content of isoflavone compounds – which possess weak estrogenic activity and have
been associated with a variety of health benefits during menopause (reduction of hot flashes, promotion of heart health and maintenance of bone density).
Basic Information:
Biochanin A (BCA) is an isoflavone mainly found in red clover with poor solubility and oral absorption that is known to have various effects, including anti-inflammatory, estrogen-like, and glucose and lipid metabolism modulatory activity, as well as cancer preventive, neuroprotective, and drug interaction effects. BCA is already commercially available and is among the main ingredients in many types of supplements used to alleviate postmenopausal symptoms in women. The activity of BCA has not been adequately evaluated in humans. However, the results of many in vitro and in vivo studies investigating the potential health benefits of BCA are available, and the complex mechanisms by which BCA modulates transcription, apoptosis, metabolism, and immune responses have been revealed. Many efforts have been exerted to improve the poor bioavailability of BCA, and very promising results have been reported. This review focuses on the major effects of BCA and its possible molecular targets, potential uses, and limitations in health maintenance and treatment.
| Alternate Names | 5,7-Dihydroxy-4′-methoxyisoflavone; 4′-Methylgenistein |
| CAS Number | 491-80-5 |
| Purity | ≥98% |
| Appearance | Powder |
| Molecular Weight | 284.27 |
| Molecular Formula | C16H12O5 |
| Physical State | Solid |
| Solubility | Soluble in water (<1 mg/ml at 25° C), chloroform, methanol, DMSO (57 mg/ml at 25° C), and ethanol (9 mg/ml at 25° C) |
| Storage | Store at 4° C |
| Melting Point | 210-213° C |
| Boiling Point | 518.6° C at 760 mmHg (Predicted) |
| Densit | 1.4 g/cm3 (Predicted) |
| Refractive Index | n20D 1.67 (Predicted) |
| pK Values | pKa: 6.5 (Predicted) |
| Ki Data | Carbonyl reductase 1: Ki= 2.03 µM (human); CYP19: Ki= 12 µM (human) |
Specification:
| Product Name | Red Clover Extract | Latin Name | Trifolium pratensel L. |
| Appearance: | Black-green or Black Powder | Specification: | 8%,20%,40%,60% |
| Active Ingredients: | Isoflavone | Part Used: | Leaf & Flower |
| Odor: | Characteristic | CAS NO. | 977150-97-2 |
| Molecular Formular | C15H10O4 | Test Method | HPLC |
| Total Isoflavones | 8% | 20% | 40% | 60% |
| Biochanin | 1.5-3% | 3-6% | 5-15% | 15-30% |
| Formononetin | 4-6% | 13-16% | 20-30% | 20-35% |
| Daidzein | 1% | 1% | 1% | 1% |
| Genistein | 1% | 1% | 1% | 1% |
Function:
1.For women, stimulate eostrogenic activity, increase fertility, and reduce “hot flashes” experienced by women during menopause
2.Anti-cancer
3.One of the most useful remedies for children with skin problems
4.Expectorant and anti-spasmodic
5.Relieve the syndrome of irritation and inflammation of urinary tract
6.Relieve constipation and help soothe inflammation of the bowel, stomach and intestines
7.Relieve tension due to stress and associated headaches
a.Red Clover Extract Improve health, anti-spasm, known for healing properties.
b.Red Clover Extract Treatment of skin diseases (such as eczema, burns, ulcers, psoriasis),
c.Red Clover ExtractTreatment of respiratory discomfort (such as asthma, bronchitis, intermittent cough)
d.Red Clover Extract Anti-cancer activity and prevention of prostate disease.
e.Red Clover Extract Red Clover Extract Most valuable of its estrogen-like effect and alleviate breast pain suffering.
f.Red clover isoflavones play in a weak estrogen, estrogen reduces the number and thus alleviate the suffering.
g.Red Clover Extract Maintain bone mineral density in postmenopausal women
h.Red Clover Extract Raise high density lipoprotein cholesterol. Red Clover Extract
Application:
1.For women, stimulate eostrogenic activity, increase fertility, and reduce hot flashes experienced by women during menopause
2.Anti-cancer
3.One of the most useful remedies for children with skin problems
4.Expectorant and anti-spasmodic
5.Relieve the syndrome of irritation and inflammation of urinary tract 6. Relieve constipation and help soothe inflammation of the bowel, stomach and intestines
XI’AN AOGU BIOTECH CO.,LTD is devoted into the research and innovation in natural nutritional supplements ingredients. Our own factory and lab with the strict quality control system to ensure quality stability and real price of Trifolium Pratense Extract Isoflavone Red Clover Extract Biochanin . At the same time, we have our own source for the raw material to make sure the production ability.